Recombinant IL12B antibody (AA 23-328)

Catalog No. ABIN7795738

This anti-IL12B antibody is a Rabbit Monoclonal antibody detecting IL12B in WB and IP. Suitable for Human.

Quick Overview for Recombinant IL12B antibody (AA 23-328) (ABIN7795738)

Target: IL12B (Interleukin 12 beta (IL12B))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This IL12B antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Clone: BLR322M

Product Details anti-IL12B Antibody

Binding Specificity: AA 23-328

Purpose: Rabbit anti-IL-12B Recombinant Monoclonal Antibody [BLR322M]

Purification: Purified

Immunogen: residues 23-328

Isotype: IgG

Application Details

Application Notes: WB,11,000,IP,6 μL/mg lysate

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1000 μg/mL

Buffer: Phosphate Buffered Saline (PBS) with 0.09 % Sodium Azide, BSA-Free

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2 - 8 °C

Expiry Date: 12 months

Target Details for IL12B

Target: IL12B (Interleukin 12 beta (IL12B))

Alternative Name: IL-12B

Background: IL-12B is a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD IL-12B, and the 35 kD subunit IL-12A. IL-12 is expressed by activated macrophages that serve as an essential inducer of Th1 cells development, and has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. [provided by RefSeq, Jul 2008, taken from NCBI Entrez Gene (Gene ID: 3593)].

Gene ID: 3593

UniProt: P29460

Pathways: JAK-STAT Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation